Given a sequence {a n } in (0,1) converging to a rational, we examine the model theoretic properties of structures obtained as limits of Shelah-Spencer graphs G(m, m -αn ). We show that in most cases the model theory is either extremely well-behaved or extremely wild, and characterize when each occurs.

Pavlovian cues predict the occurrence of motivationally salient outcomes, thus serving as an important trigger of approach and avoidance behavior. The amygdala is a key substrate of Pavlovian conditioning, and the nature of its contribution varies by the motivational valence of unconditioned stimuli. The literature on aversive Pavlovian learning supports a serial-processing model of amygdalar function, while appetitive studies suggest that Pavlovian associations are processed through parallel circuits in the amygdala. It is proposed that serial and parallel forms of information (...) processing can be attributed to differential recruitment of amygdalar nuclei, with emphasis placed on the lateral amygdala. (shrink)

In this paper we use an experimental approach to investigate how linguistic conventions can emerge in a society without explicit agreement. As a starting point we consider the signaling game introduced by Lewis. We find that in experimental settings, small groups can quickly develop conventions of signal meaning in these games. We also investigate versions of the game where the theoretical literature indicates that meaning will be less likely to arise—when there are more than two states for actors to transfer (...) meaning about and when some states are more likely than others. In these cases, we find that actors are less likely to arrive at strategies where signals have clear conventional meaning. We conclude with a proposal for extending the use of the methodology of experimental economics in experimental philosophy. (shrink)

The assumption that the concept of phenomenal consciousness is pretheoretical is often found in the philosophical debates on consciousness. Unfortunately, this assumption has not received the kind of empirical attention that it deserves. We suspect that this is in part due to difficulties that arise in attempting to test folk intuitions about consciousness. In this article we elucidate and defend a key methodological principle for this work. We draw this principle out by considering recent experimental work on the topic by (...) Joshua Knobe and Jesse Prinz (2008). We charge that their studies do not establish that the folk have a concept of phenomenal consciousness in part because they compare group agents to individuals . The problem is that group agents and individuals differ in some significant ways in terms of functional organization and behavior. We propose that future experiments should establish that ordinary people are disposed to ascribe different mental states to entities that are given behaviorally and functionally equivalent descriptions. (shrink)

Recent work in cognitive science of religion (CSR) is beginning to converge on a very interesting thesis—that, given the ordinary features of human minds operating in typical human environments, we are naturally disposed to believe in the existence of gods, among other religious ideas (e.g., seeAtran [2002], Barrett [2004; 2012], Bering [2011], Boyer [2001], Guthrie [1993], McCauley [2011], Pyysiäinen [2004; 2009]). In this paper, we explore whether such a discovery ultimately helps or hurts the atheist position—whether, for example, it lends (...) credence to atheism by explaining away religious belief or whether it actually strengthens some already powerful arguments against atheism in the relevant philosophical literature.We argue that the recent discoveries of CSR hurt, not help, the atheist position—that CSR, if anything, should not give atheists epistemic assurance. (shrink)

Highly idealized models, such as the Hawk-Dove game, are pervasive in biological theorizing. We argue that the process and motivation that leads to the introduction of various idealizations into these models is not adequately captured by Michael Weisberg’s taxonomy of three kinds of idealization. Consequently, a fourth kind of idealization is required, which we call hypothetical pattern idealization. This kind of idealization is used to construct models that aim to be explanatory but do not aim to be explanations.

Mental health chatbots (MHCBs) designed to support individuals in coping with mental health issues are rapidly advancing. Currently, these MHCBs are predominantly used in commercial rather than clinical contexts, but this might change soon. The question is whether this use is ethically desirable. This paper addresses a critical yet understudied concern: assuming that MHCBs cannot have genuine emotions, how this assumption may affect psychotherapy, and consequently the quality of treatment outcomes. We argue that if MHCBs lack emotions, they cannot have (...) genuine (affective) empathy or utilise countertransference. Consequently, this gives reason to worry that MHCBs are (a) more liable to harm and (b) less likely to benefit patients than human therapists. We discuss some responses to this worry and conclude that further empirical research is necessary to determine whether these worries are valid. We conclude that, even if these worries are valid, it does not mean that we should never use MHCBs. By discussing the broader ethical debate on the clinical use of chatbots, we point towards how further research can help us establish ethical boundaries for how we should use mental health chatbots. (shrink)

Scholars have suggested that leaders’ ethical failures at the beginning of the twenty-first century have raised awareness about the importance of ethical leadership (EL). Yet, there has been no systematic effort to evaluate whether this awareness indeed led to changes in EL or how followers react to this leadership style over time. To address this gap, we examine the evolution in EL means, variability, and its associations with follower outcomes between 2004 and 2019. Our cross-temporal meta-analysis included 359 independent samples (...) from 314 studies published between 2005 and 2020 and focused on followers’ ratings of their leaders using the Ethical Leadership Scale (ELS; Brown et al., in Organizational Behavior and Human Decision Processes, 97(2), 117–134, 2005). Using cubic spline meta-regressions, our results indicated no global changes in EL mean levels and variability across the 15-year period. Nevertheless, country-level comparisons revealed different EL-trends in China (i.e. decrease) versus the United States (i.e. stable), and further moderation analyses highlighted the role of cultural value dimensions and national corruption rates. Finally, we also found that the relationship between EL and desirable follower outcomes (e.g. organizational citizenship behavior) became gradually stronger over time on a global level. These results provide a solid empirical basis to evaluate cross-temporal trends in EL and its (changing) impact on follower outcomes across the globe. (shrink)

In the United States, it is common for people entering christian organizations to receive explanation of what the Bible means before being handed the book and asked to read. Religious ideological transfer stems from this strict codification, and the Story of Abraham highlights the effective blending between original text and interpretation. Recognizing how the Story of Abraham calls for, as Kierkegaard suggested, a suspension of the ethical for obedience, it justifies entrance into a religious state of exception, a fully subjective (...) moment into which the sole sovereign of “divine will” is the self. The social ramifications, beyond a-logical relativism, involve the historic and continued justification of religious otherization and dehumanization, shrined in a belief of divinity. In contemporary debate, the religious hunker down, entrenching themselves within their ideology, while many in deconstructivist camps want to tear these institutions apart. I suggest a middle-ground: a radical reinterpretation — through philosophical, linguistic and literary theory methods — of the Story of Abraham as a narrative reflecting the Tower of Babel motif, to work within the christian ideological system to create strategic biblical interpretations for positive social effect. (shrink)

How do newborns learn to recognize objects? According to temporal learning models in computational neuroscience, the brain constructs object representations by extracting smoothly changing features from the environment. To date, however, it is unknown whether newborns depend on smoothly changing features to build invariant object representations. Here, we used an automated controlled-rearing method to examine whether visual experience with smoothly changing features facilitates the development of view-invariant object recognition in a newborn animal model—the domestic chick. When newborn chicks were reared (...) with a virtual object that moved smoothly over time, the chicks created view-invariant representations that were selective for object identity and tolerant to viewpoint changes. Conversely, when newborn chicks were reared with a temporally non-smooth object, the chicks developed less selectivity for identity features and less tolerance to viewpoint changes. These results provide evidence for a “smoothness constraint” on the development of invariant object recognition and indicate that newborns leverage the temporal smoothness of natural visual environments to build abstract mental models of objects. (shrink)

This article proposes an evolution of Edmund Husserl’s transcendental epoché by integrating P. R. Sarkar’s Tantra sádhaná, which engages ipseity as both the subject and the object of consciousness. First, it explores some of the recent philosophical and scientific obstacles that confound the transcendental reduction. Following this, an East-West trajectory for Husserl’s first science of consciousness is examined by combining Sarkar’s 3 shuddhis in pratyáhára, effecting an experience of noumenal consciousness. Combining Husserl’s phenomenology with Sarkar’s spiritual praxis reinvigorates the transcendental (...) epoché and emphasizes practice in a field both undermined by logical positivism and dominated by the scholasticism of Husserl’s protégés. Furthermore, the efficacy of an East-West approach is contextualized in view of Husserl’s admiration of Buddhism and Sarkar’s cognitive cosmology. (shrink)

Prevailing theories of consciousness may be characterized as either a physicalist view of mind with material building blocks that grow in complexity unto an emergent conscious experience, or as a dualistic model in which mind-body interaction is taken as the interface of conscious intent and unconscious bodily processing. Roger Penrose supports a model of consciousness that goes beyond dualism by adding a third domain [19]. The Three World model describes interconnected yet independent aspects of consciousness: Physical, Mental & Platonic. These (...) three worlds are grounded in the three axioms of quantum mechanics: measurement, superposition and entanglement. The Mental World corresponds to the superposition principle in which all possible future realities are superposed as potentials before a choice is made. The superposition is analogous to the choices we make everyday. In the Physical World, the measurement principles states that the quantum system must collapse the superposed possibilities into a single actuality. The most peculiar phenomenon in quantum mechanics is entanglement. Quantum systems may be entangled in a timeless and spaceless way such that they will still be connected despite separation in space or time. The Platonic World is akin to entanglement, because mathematics and conceptual forms are unchanging regardless of space or time. Finally, a new model called Fractal Trialism is proposed which describes how there is a nested trialism within each of the three worlds in order to elaborate their interconnectedness. This model describes digital computers, quantum computers and shared experience. Normal 0 false false false EN-US X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;} Normal 0 false false false EN-US X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;}. (shrink)

It has long been appreciated that the brain is oscillatory 1. Early measurements of brain electrophysiology revealed rhythmic synchronization unifying large swaths of the brain. The study of neural oscillation has enveloped cognitive neuroscience and neural systems. The traditional belief that oscillations are epiphenomenal of neuron spiking is being challenged by intracellular oscillations and the theoretical backing that oscillatory activity is fundamental to physics. Subjective experience oscillates at three particular frequency bands in a cognitive triad: perception at 5 Hz, action (...) at 2 Hz, and attention at 0.1 Hz. This triad functions as a means of information flow across scales of magnitude in a biological fractal. The _Homunculus Solution _is proposed in which mental experience occurs at fixed scales of biology. The mind is composed of minds, perceived as "the voices in your head." Each voice has voices inside its head to increasingly microscopic scales, forming an interactive fractal of subjective experience. Normal 0 false false false EN-US X-NONE X-NONE. (shrink)

It is a prevalent, if not popular, thesis in the metaphysics of belief that facts about an agent’s beliefs depend entirely upon facts about that agent’s underlying credal state. Call this thesis ‘credal reductivism’ and any view that endorses this thesis a ‘credal reductivist view’. An adequate credal reductivist view will accurately predict both when belief occurs and which beliefs are held appropriately, on the basis of credal facts alone. Several well-known—and some lesser known—objections to credal reductivism turn on the (...) inability of standard credal reductivist views to get the latter, normative, results right. This paper presents and defends a novel credal reductivist view according to which belief is a type of “imprecise credence” that escapes these objections by including an extreme credence of 1. (shrink)

Rosamond Rhodes' evaluation of modern American research ethics emphasizes a need to shift from a protectionist understanding of human subjects to one that focuses more on the conduct of research in...

In this article I critique Kathleen Slaney and Michael Maraun’s (2005) addition to the ongoing philosophical charge that neuroscientific writing often transgresses the bounds of sense. While they sometimes suggest a minimal, cautious thesis–that certain usage can generate confusion and in some cases has–they also bandy about charges of meaninglessness, conceptual confusion, and nonsense freely. These charges rest on the premise that terms have specific correct usages that correspond with Slaney and Maraun’s sense of everyday linguistic practice. I challenge this (...) premise. I argue that they have not shown that there are such specific correct usages; and, further, that even if they had, they fail to justify that their definitions are the correct ones. (shrink)

The social principle of subsidiarity, both regarding the federalism debate in North America and the principle’s role in the formation of the European Union, has garnished increased attention in recent years. In this paper I will argue that if one looks for the historical seed of the principle of subsidiarity in Aristotle—as many authors do—then attention should fall more properly on his analysis of practical reasoning in Book VI of the Nicomachean Ethics than on Book I of the Politics. The (...) treatment of practical reasoning more aptly explains the need for the principle of subsidiarity and, indeed, averring that it is based on an Aristotelian sense of autonomy is misplaced at best and dangerous at worst. (shrink)

This paper argues against the current presentation of Aquinas’s conception of pagan virtue because that conception fails to take into account the full weight of the corruption of the goods of nature on which the virtuous unbeliever must found his good acts. I go on to establish that postlapsarian man is in too capricious a position realistically to maintain a prolonged life of virtue. I conclude that while Aquinas’s conception of virtue renders a much more pessimistic picture of the virtuous (...) pagan than recent literature has presented, his reputed theoretical optimism is correct, but is founded on his conception of God’s help. Thus, it makes little sense to have a philosophical discussion about Aquinas’s notion of pagan virtue, because it is impossible to separate the «gifts of God» from «the unbeliever.». (shrink)

Despite the prevalence of beliefs across religions regarding repentance and divine forgiveness and their recognition in theoretical and religious studies, these constructs are relatively understudied phenomena in the social sciences. Furthermore, in recent years, multiple scholars have argued for the need for research to systematically study and highlight the experience and processes of repentance and divine forgiveness. Subsequently, this study explored processes of repentance, antecedents and motivations of repentance, resources to aid in repentance, and outcomes of repentance that should be (...) further examined. This analysis was done using in-depth qualitative interviews with 15 emerging adult religious exemplars identifying with the Church of Jesus Christ of Latter-day Saints. The authors used NVivo 12 and team-based qualitative coding processes to identify themes. Repentance processes included personal change, took various lengths of time, were a part of participants’ religious identity, were recurrent processes, and were influenced by participants’ view of God. Antecedents and motivations included religious practices and rituals, emotions, interpersonal interactions, and their relationship with God. Resources that aided in repentance included religious practices and rituals, interpersonal relationships, and a relationship with God. Finally, participants reported experiencing personal changes in their behavior and character, positive emotions (including feelings of divine forgiveness), improved interpersonal relationships, and a better relationship with God. These processes align with some previously discovered and theorized findings on repentance, contribute a number of novel findings, and offer future direction regarding the motivations, resources, and transformative experiences that participants reported in their personal repentance and experience of forgiveness. (shrink)

The present study examined forgetting and recovery of narrative passages varying in emotional intensity, using what we refer to as the “dropout” method. Previous studies of this dropout procedure have used word lists as to-be-remembered material, but the present experiments used brief story vignettes with one-word titles . These vignettes showed a strong dropout forgetting effect in free recall. Both text and picture cues from the vignettes eliminated the forgetting effect on a subsequent cued recall test. Vignette-related pictures in an (...) incidental picture naming task, however, triggered little recovery of initially forgotten vignettes, as shown on a post-test. The results extend findings of large forgetting and memory recovery effects to materials that are more naturalistic than word lists. The findings also show that picture cues, which trigger strong memory recovery effects on a direct test of memory, had little effect on recovery when cues were encountered incidentally. (shrink)

In contrast to scholars and signers in the nineteenth century, William Stokoe conceived of American Sign Language (ASL) as a unique linguistic tradition with roots in nineteenth-centurylangue des signes française, a conception that is apparent in his earliest scholarship on ASL. Stokoe thus contributed to the theoretical foundations upon which the field of sign language historical linguistics would later develop. This review focuses on the development of sign language historical linguistics since Stokoe, including the field's significant progress and the theoretical (...) and methodological problems that it still faces. The review examines the field's development through the lens of two related problems pertaining to how we understand sign language relationships and to our understanding of cognacy, as the term pertains to signs. It is suggested that the theoretical notions underlying these terms do not straightforwardly map onto the historical development of many sign languages. Recent approaches in sign language historical linguistics are highlighted and future directions for research are suggested to address the problems discussed in this review. (shrink)

As the capabilities of Artificial Intelligence (AI) have increased over recent years, so have the challenges of how to govern its usage. Consequently, prominent stakeholders across academia, government, industry, and civil society have called for states to devise and deploy principles, innovative policies, and best practices to regulate and oversee these increasingly powerful AI tools. Developing a robust AI governance system requires extensive collective efforts throughout the world. It also raises old questions of politics, democracy, and administration, but with the (...) new challenges posed by AI's growing influence on markets, governing structures, international relations, healthcare, science, and political activism. The Oxford Handbook of AI Governance delineates the scope of these issues and addresses the key questions of AI governance. Across forty-nine chapters, organized in nine major sections, the Handbook covers the theoretical and ethical foundations of AI governance, different frameworks for developing a governance structure for AI, practical perspectives on AI governance in different policy domains, economic analyses of AI governance, and concrete lessons about the impact of AI governance domestically and internationally. Chapter authors come from a wide set of disciplines, areas of study, and cultural backgrounds, providing a global perspective on AI governance. (shrink)

Until recently, retention of introns in mature mRNAs has been regarded as a consequence of mis‐splicing. Intron‐retaining transcripts are thought to be non‐functional because they are readily degraded by nonsense‐mediated decay. However, recent advances in next‐generation sequencing technologies have enabled the detection of numerous transcripts that retain introns. As we review herein, intron‐retaining mRNAs play an essential conserved role in normal physiology and an emergent role in diverse diseases. Intron retention should no longer be overlooked as a key mechanism that (...) independently reduces gene expression in normal biology. Exploring its contribution to the development and/or maintenance of diseases is of increasing importance. (shrink)

After nearly three decades of scientific research, digital mental health (DMH) is having its moment. Millions of dollars of venture capital funding are entering this space (Shah and Berry 2021; Wan...

Background: Parkinson’s disease is a neurodegenerative disease in which the progressive loss of dopaminergic neurons leads to initially sporadic and eventually widespread damage of the nervous system resulting in significant musculoskeletal and cognitive deterioration. Loss of motor function alongside increasing cognitive impairment is part of the natural disease progression. Gait is often considered an automatic activity; however, walking is the result of a delicate balance of multiple systems which maintain the body’s center of mass over an ever-changing base of support. (...) It is a complex motor behavior that requires components of attention and memory to prevent falls and injury. In addition, evidence points to the critical role of salient visual information to gait adaptability. There is a growing understanding that treatment for PD needs to address movement as it occurs naturally and walking needs to be practiced in more complex environments than traditional therapy has provided.MethodsIn this single-blinded randomized-controlled pilot study, an immersive treadmill training was piloted to determine feasibility and preliminary efficacy on gait and cognition in people with PD. Eighteen participants with Hoehn and Yahr stages I-III PD were randomized to either an intervention or a waitlist control group. Following baseline data collection, the intervention group trained for 30 min, three times/week for 4 weeks on a split belt treadmill combined with a first-person immersive video game targeting visuospatial skills and working memory. Assessment was repeated after 4 weeks of training for the experimental group and 1-month after baseline for the control group. Primary motor outcomes were captured with the APDM Opal sensors during 6 MWT, TUG, and TUG Cognitive. Secondary outcomes of cognition were measured with the Montreal Cognitive Assessment, Verbal Fluency and the Symbol Digit Modality Test. Within subject differences were calculated using the Wilcoxon Signed Ranked Test and between subject comparisons were analyzed using the Mann Whitney U-test.ResultsThis novel treadmill training program was well-tolerated with all participants in the intervention group completing 4 weeks of training three times a week without any adverse effects. After immersive cognitive motor training, the experimental group made clinically relevant improvements in gait speed and walking distance during the 6 MWT while members of the control group showed no change or decreased gait speed and walking distance over the 1-month trial. In addition, the experimental group demonstrated significant improvement for the TUG Cognitive and those changes were greater than the control group. The experimental group also improved scores on MoCA and SDMT cognitive outcome measures while the control group did not.ConclusionThe use of immersive gaming technology to engage specific areas of cognition related to gait is feasible in PD. The treadmill training program paired with a customized interactive video game improved walking velocity in addition to non-significant but consistent improvements in other gait measures and cognitive performance in participants with early to mid-stage PD. (shrink)

Deamination of adenosine in RNA to form inosine has wide ranging consequences on RNA function including amino acid substitution to give proteins not encoded in the genome. What determines which adenosines in an mRNA are subject to this modification reaction? The answer lies in an understanding of the mechanism and substrate recognition properties of adenosine deaminases that act on RNA (ADARs). Our recent publication of X‐ray crystal structures of the human ADAR2 deaminase domain bound to RNA editing substrates shed considerable (...) light on how the catalytic domains of these enzymes bind RNA and promote adenosine deamination. Here we review in detail the deaminase domain‐RNA contact surfaces and present models of how full length ADARs, bearing double stranded RNA‐binding domains (dsRBDs) and deaminase domains, could process naturally occurring substrate RNAs. (shrink)

In a recent article Humphreys has developed an intriguing proposal for making sense of emergence. The crucial notion for this purpose is what he calls "fusion" and his paradigm for it is quantum nonseparability. In what follows, we will develop this position in more detail, and then discuss its ramifications and limitations. Its ramifications are quite radical; its limitations are substantial. An alternative approach to emergence that involves quantum physics is then proposed.